La maladie d'Alzheimer est une maladie neurodégénérative caractérisée par l'agrégation de bêta‐amyloïde (amyloïde β ou Aβ) dans les plaques extracellulaires et par l’hyperphosphorylation de la protéine tau dans les enchevêtrements neurofibrillaires intracellulaires. De nombreuses autres protéines sont également associées à cette pathologie.
Newmarket Scientific fournit des anticorps primaires ciblant un grand nombre de protéines associées à la maladie d'Alzheimer et en ajoute régulièrement à partir des dernières publications. L'identification des nouvelles cibles émergentes pour développer des anticorps, permet de mieux servir la recherche sur la maladie d'Alzheimer.
Les anticorps primaires proposés ont des réactivités diverses (Humain, Souris, Rat, Singe) et sont validés pour l’ImmunoHistoChimie (IHC), le Western Blot (WB), l’ImmunoFluorescence (IF), l’ImmunoCytoChimie (ICC), l’ELISA ou la Cytométrie en flux (FC).
Vous trouverez ci-dessous la liste des cibles de la maladie d'Alzheimer dont les anticorps primaires sont disponibles à la vente.
ApoE (Apolipoprotein E) Antibodies
Affinity |
AF5178 |
Internal region |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity |
BF0404 |
Prtn fragment |
Hu |
WB|IHC|IF|E|FC |
Affinity |
DF4797 |
Internal region |
Hu|Ms|Rt |
WB|IF|ICC,E |
APP (Amyloid precursor protein) and phospho-APP Antibodies
Affinity |
AF7687 |
C-terminal |
Hu|Ms|Rt |
WB |
Affinity |
DF6012 |
N-termina |
Hu|Ms|Rt |
WB|IHC|IF |
Affinity |
DF7218 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF |
Affinity |
AF6084 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity (Thr743/668) |
AF3084 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|IF |
Affinity (Thr729) |
AF8461 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IF |
Affinity (Thr757) |
AF7187 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
ACE (Angiotensin converting enzyme) Antibodies
NS Reagents |
AB19-10096 |
Central region |
Hu|Ms|Rt |
WB|IHC |
Affinity |
AF5197 |
Peptide |
Hu|Ms|Rt |
WB|IHC|E |
BACE Antibodies
Affinity |
DF7594 |
C-terminal |
Hu|Ms|Rt |
WB|E |
Affinity |
DF7939 |
C-terminal |
Hu |
WB|E |
Affinity (Ser498) |
AF8003 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
BIN1 (Bridging INtegrator 1) Antibodies
NS Reagents |
AB19-10095 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF. |
CD2AP (CD2-associated protein) Antibodies
NS Reagents |
AB19-10100 |
Central region |
Hu |
WB |
Affinity |
DF2298 |
Peptide |
Hu|Ms |
WB|E |
CDK5 (Cyclin-dependent-like kinase 5) Antibodies
NS Reagents |
AB20-10126 |
N-terminal |
Hu|Ms|Rt|Mk |
WB|IHC|IF |
Affinity |
AF6371 |
N-terminal |
Hu|Ms|Rt|Mk |
WB|IHC|IF|E |
Affinity |
BF0121 |
Prtn fragment |
Hu|Ms|Rt|Mk |
WB|IHC|IF|E |
Affinity (Tyr15) |
AF3371 |
Phosphopeptide |
Hu|Ms|Rt|Mk |
WB|IF |
Affinity (Ser159) |
AF8366 |
Phosphopeptide |
Hu|Rt|Mk |
WB|IHC|IF|E|FC |
CYP46A1/Cytochrome P450 46A1 Antibodies
NS Reagents |
AB19-10097 |
N-terminal |
Hu|Ms|Rt |
WB|IHC |
Affinity |
DF8926 |
peptide |
Hu|Ms |
EB|E |
DKK1/Dickkopf WNT signaling pathway inhibitor 1 Antibodies
NS Reagents |
AB19-10101 |
Full length |
Hu|Ms |
WB |
Affinity |
AF4600 |
Peptide |
Hu|Ms|Rt |
WB|IHC |
Affinity |
BF0699 |
Prtn fragment |
Hu |
WB|E |
Affinity (Ser140) |
AF4300 |
Phosphopeptide |
Hu|Ms |
WB |
Antibodies to EAAT2 Antibodies
NS Reagents |
AB19-10103 |
C-terminal |
Hu|Ms|Rt |
IHC |
Affinity |
DF8535 |
Central region |
Hu|Ms|Rt |
WB |
GPHN/Gephyrin Antibodies
NS Reagents |
AB19-10098 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF |
Affinity |
DF9531 |
Central region |
Hu|Ms |
WB|IHC|E |
Antibodies to Histone deacetylase 6 Antibodies
NS Reagents |
AB19-10114 |
recombinant protein |
Hu|Ms |
IHC|IF |
Affinity |
AF0594 |
N-terminal |
Hu|Ms |
WB|IHC|IF|E |
Affinity |
AF5359 |
C-terminal |
Hu|Ms |
WB|IHC|E |
Affinity |
DF6582 |
N-terminal |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity (Ser22) |
AF3485 |
Phosphopeptide |
Hu|Ms |
WB|IHC|IF|E |
IBA1/AIF-1 Antibodies
Affinity |
DF6442 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|E |
Affinity |
DF7214 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity |
DF7552 |
C-terminal |
Hu|Rt |
WB|IHC|E |
KIF5A/Kinesin heavy chain isoform 5A Antibodies
NS Reagents |
AB19-10081 |
C-terminal |
Hu|Ms|Rt |
WB|IHC |
NS Reagents |
AB19-10082 |
C-terminal |
Hu|Ms|Rt |
IHC |
Lipocalin 2 Antibodies
NS Reagents |
AB20-10130 |
Full length |
Hu|Ms|Rt |
WB|IF |
NS Reagents |
AB20-10131 |
Peptide |
Hu|Ms |
WB|IHC |
NS Reagents |
AB20-10132 |
Peptide |
Hu |
WB|IHC |
Affinity |
DF6816 |
Peptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity |
DF7232 |
Peptide |
Hu|Ms|Rt |
WB|IHC|E |
Nicastrin Antibodies
Affinity |
DF6242 . |
C-terminal . |
Hu|Ms|Rt |
WB|IHC|E |
OLIG2/Oligodendrocyte transcription factor Antibodies
NS Reagents. |
AB19-10080 |
N-terminal |
Hu|Ms |
W|IHC |
Affinity |
DF8004 |
Central region. |
Hu |
WB|E |
PSEN1 (Presenilin 1) Antibodies
Affinity |
AF0245 |
Internal region |
Hu|Ms |
WB|IHC|IF|E |
Affinity |
DF6910 |
Internal region |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity (Ser353) |
AF8304 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IF|E |
PSEN2 (Presenilin 2) Antibodies
Affinity |
AF0245 |
Internal region |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser199) |
AF8093 |
Phosphopeptide |
Hu|Ms|Rt |
WB |
SFPQ (Splicing factor, proline-glutamine-rich) Antibodies
NS Reagents. |
AB18-10072 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF |
Affinity |
DF12317 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF|E |
Tau (MAPT/Microtubule-Associated Protein Tau) Antibodies
Affinity |
DF6244 |
C-terminal |
Hu|Ms|Rt |
WB|E |
Affinity |
AF6141 |
Internal region |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Ser199) |
AF2418 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser202) |
AF2419 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser214) |
AF3141 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser235) |
AF3142 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser262) |
AF3151 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Ser356) |
AF3143 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity (Ser396) |
AF3148 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Ser404) |
AF3144 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser416) |
AF2420 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser422) |
AF3145 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Thr181) |
AF3149 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Thr205) |
AF3150 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Thr212) |
AF3146 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Thr231) |
AF3147 |
Phosphopeptide |
Hu|Ms|Rt |
WB|E |
TDP43 (TAR DNA-binding protein 43) Antibodies
NS Reagents |
AX17-10010 |
C-terminal |
Hu |
WB|IHC|IF|E |
NS Reagents |
AB18-10049 |
N-terminal |
Hu|Ms|Rt |
WB|IHC|IF|IP |
Affinity (Ser209) |
AF7365 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity |
AF7865 |
C-terminal |
Hu|Ms|Rt |
WB|E |
Affinity |
DF2968 |
C-terminal |
Hu|Ms|Rt |
WB|E |
Affinity |
DF6317 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|E |
Tyrosine hydroxylase (TH) Antibodies
Affinity |
AF6113 |
Full length |
Hu|Rt|Ms |
WB|IHC |
Affinity (Ser19) |
AF3112 |
Phosphopeptide |
Hu|Rt|Ms |
WB|IHC|IF |
Affinity (Ser19) |
AF3115 |
Phosphopeptide |
Hu|Rt|Ms |
WB|IHC|IF|E. |
Affinity (Ser31) |
AF3113 |
Phosphopeptide |
Hu|Rt|Ms |
WB|IHC|IF|E |
Affinity (Ser40) |
AF3114 |
Phosphopeptide |
Hu|Rt|Ms |
WB|IHC|IF|E |
USP10 (Ubiquitin-specific protease 10) Antibodies
NS Reagents |
AB19-10115 |
C-terminal |
Hu|Ms |
WB|IF |
Affinity |
DF8061 |
N-terminal |
Hu|Ms|Rt |
WB|E |
YWHAQ (14-3-3 protein theta) Antibodies
NS Reagents |
AB19-10102 |
Full length |
Hu|Ms|Rt |
WB|IHC |
Affinity |
DF3494 |
Peptide |
Hu|Ms|Rt |
WB|IF |
Affinity |
DF7016 |
Peptide |
Hu|Ms|Rt |
WB|IF|E |