Lymphomas | CD45 | CD20 | CD79a | bcl-2 | bcl-6 | CD10 | CD23 | Cyclin D1 | PAX-5 | BOB.1 | Oct-2 | PU.1 | p27/Kip1 | IgD | MUM1 | T-beta | TRAcP | Annexin A1 | CD5 | CD43 | CD3 | ZAP-70 | CD25 | FOXP1 | TCL1 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Follicular | + | + | + | + | + | + | – | – | + | + | + | + | + | + | – | – | – | – | – | – | – | – | - | + | |
CLL/SLL | + | + | + | + | – | – | + | – | + | + | + | + | + | + | + | + | – | – | + | + | – | +/- | + | ||
Mantle Cell | + | + | + | + | – | – | – | + | + | + | + | + | + | + | – | – | – | – | + | + | – | – | – | -/+ | + |
Marginal Zone BCL | + | + | + | + | – | – | – | – | + | + | + | + | + | -/+ | + | + | +/- | – | – | – | – | – | - | ||
Lymphoplasmacytic | + | + | + | + | – | – | – | – | + | + | + | - | + | + | – | – | – | – | – | - | - | + | |||
Diffuse Large Cell Lymphoma | + | + | + | + | + | – | – | – | + | + | + | + | – | – | + | – | – | – | – | – | - | + | +/- | ||
Burkitt Lymphoma | + | + | + | – | + | + | – | – | + | – | – | – | - | – | - | + | - | - | + | ||||||
Hairy Cell Leukemia | + | + | + | + | – | – | – | – | + | - | - | + | + | + | - | - | - | + |
Lymphomas | CD45 | CD2 | CD3 | CD4 | CD5 | CD7 | CD8 | CD25 | CD45RO | PD-1 | CD56 | CD57 | Perforin | Granzyme_B | TCL1 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angioblastic | + | + | + | + | + | + | +/- | + | + | + | |||||
Lymphoblastic | + | +/- | + | +/- | + | + | +/- | + | + | – | - | ||||
Subcutaneous Panniculitic | + | + | + | – | + | + | +/- | – | + | – | – | + | + | ||
Lennert’s | + | + | + | – | + | - | + | + | – | _ | |||||
NK-Type | + | + | + | – | – | + | – | + | + | – | +/- | +/- | – | + | + |
Cutaneous | + | + | + | + | – | + | – | – | – | – | + | + | - | ||
Peripheral | + | + | + | + | + | – | – | + | + | – | – | – | – | – | – |
Mycosis Fungoides | + | + | + | + | + | – | – | + | + | – | – | - |
Leukemia | MPO | CD68 | Factor VIII | CD61A | Hemoglobin A | BOB.1 | Oct-2 | Glycophorin A | Spectrin | CD34 | CD43 | CD74 | CD45 | Lysozyme | CD138 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acute Myeloid, M0 | – | – | – | – | – | – | – | – | – | + | + | + | + | + | + |
Myeloblast, M1&2 | + | + | – | – | – | - | - | - | + | + | + | + | + | ||
Promyelocytic, M3 | + | + | – | – | – | + | + | – | + | - | |||||
Myelomonocytic, M4 | + | + | – | – | – | – | + | – | – | + | + | + | + | + | |
Monoblastic, M5 | + | + | – | – | – | – | + | – | – | – | + | + | + | + | |
Acute Myeloid, M6 | + | – | – | – | – | - | + | + | – | - | + | ||||
Megakaryocytic, M7 | – | – | + | + | – | +/- | – | - | - | ||||||
Megakaryoblast | + | + | + | + | - |
Lymphomas | TDT | CD10 | PAX-5 | CD20 | CD19 | CD3 | CD5 | CD7 | CD117 | CD74 |
---|---|---|---|---|---|---|---|---|---|---|
Lymphoblastic BCL | + | +/- | + | +/- | + | – | – | – | – | + |
Lymphoblastic TCL | + | + | – | – | – | + | +/- | + | – | – |
Lymphomas | CD138 | CD79a | EMA | MUM1 | CD56 | Cyclin D1 | CD43 | CD20 | CD19 |
---|---|---|---|---|---|---|---|---|---|
Plasma Cell Tumor | + | + | + | + | + | – | – | – | – |
Lymphomas | CD68 | S-100 | CD1a | Lysozyme | CD21/CD35 | FDC | PD-1 |
---|---|---|---|---|---|---|---|
Reactive | + | – | – | + | – | – | – |
Langerhans | + | + | + | + | – | – | – |
Sinus Histiocytosis with | + | + | – | + | – | – | – |
Massive Lymphadenopathy | |||||||
Follicular Dendritic Cell Tumor | – | – | – | – | + | + | + |
Dermatopathic Lymphadenitis | – | + | + | + | – | – | – |
Lymphomas | CD45 | CD4 | CD68 | Lysozyme | CD163 | Factor XIIIa | CD20 | CD3 |
---|---|---|---|---|---|---|---|---|
Histiocytic Lesions | + | + | + | + | + | + | – | – |
Lymphomas | S-100 | CD68 | Vimentin | Lysozyme | CD1a | Factor XIIIa | HAM56 |
---|---|---|---|---|---|---|---|
Juvenile Xanthogranuloma | – | + | + | + | – | + | + |
Langerhans Cell Histiocytosis | + | + | + | + | + | – | + |
Dermatobroma | – | + | + | – | – | + | + |
Lymphomas | IgA | IgG | IgD | IgM | Kappa | Lambda |
---|---|---|---|---|---|---|
Secretory Meningioma | + | – | – | + | ||
Microvillous Lymphoma | – | – | – | + | ||
Cutaneous Lymphoma | – | – | – | – | ||
Myeloma | + | + | +/- | – | + | + |
Diffuse LBCL | – | + | – | + | + | + |
Marginal Zone Lymphoma | – | – | -/+ | + | + | + |
SLL/CLL | – | – | + | + | + | + |
Lymphomas | CD20 | CD79a | CD19 |
---|---|---|---|
Pro-B | – | + | + |
Pre-B | – | + | + |
Late Pre-B | + | + | + |
Mantle B-cells | + | + | + |
Centroblastic | + | + | + |
Centrocytic | + | + | + |
Plasmablasts | – | + | – |
Plasma cells | – | + | – |
Lymphomas | CD20 | CD45R | CD43 | CD45RO | CD3 |
---|---|---|---|---|---|
Low Grade BCL | + | + | – | – | – |
High Grade BCL | + | + | – | – | – |
Low Grade TCL | – | – | + | + | + |
High Grade TCL | – | – | + | + | +/- |
Lymphomas | bcl-2 | bcl-6 | CD10 | Ki-67 |
---|---|---|---|---|
Follicular Lymphoma | + | + | + | – |
Reactive Follicles | – | + | + | + |
Lymphomas | Tryptase | CD117 | CD25 | CD163 | CD2 |
---|---|---|---|---|---|
Mastocytosis | + | + | + | – | + |
Reactive Mast Cells | + | + | – | + | – |
Myelomastocytic Leukemia | + | + | – | - |
Lymphomas | MPO | CD34 | CD117 | CD68 | Hemoglobin A |
---|---|---|---|---|---|
Chronic Myelogenous Leukemia | + | -/+ | +/- | + | – |
Chronic Idiopathic Myelofibrosis | + | +/- | -/+ | - | |
Myelodysplastic Syndrome | + | -/+ | - | ||
Myelodysplastic / Myeloproliferative Disorders | + | – | – | + | – |
Mastocytosis | + | – | + | - | |
Erythroid Disorders | +/- | – | – | -/+ | + |
Splenic Lymphoma | -/+ | – | – | - | |
Acute Myeloid Leukemia | + | + | + | + | – |
Polycythemia Vera | + | + | + |